Performs both Active and Passive Avoidance Testing
Supports operation of up to 30 boxes
Standard visual and acoustical stimuli
Cage made of Makrolon
Avoidance Cage Dimensions: 19"L x 9"W x 10.75"H (48cm x 23cm x 27cm)
Motion Detection Method: Multiple Infrared Beams
Electric Stimulus
Cage Material: Makrolon & Stainless Steel
Stimulus Voltage: 162 to 200 volts
Shock Method: True Constant-Current, 100ms pulse every 250ms (4Hz)
Shock Current: Range of 0-1000uA. 11 fixed set-points (0-10) factory selected at: (0, 100, 200, 300, 400, 500, 600, 700, 800, 900, 1000uA) automatic calibration.
Stimulus Current Regulation: 1% for 0-163 KOhms.
Audio Stimulus
Sound Frequency: Range of 200-13,000Hz in 100Hz steps with automatic calibration
Sound Volume: Range of Mute-115dB. 11 adjustable set-points (0-10) factory selected at: (Mute, 70, 75, 80, 85, 90, 95, 100, 105, 110, 115dB) adjustable ±3dB
Light Stimulus
Lamp: Phillips Luxeon K2 LED, warm white output from 0-150Lux
Lamp Intensity: Range of 0-150Lux. 11 adjustable set-points (0-10) factory selected at: (0, 15, 30, 45, 60, 75, 90, 105, 120, 135, 150Lux) adjustable ±10Lux
Click on any of the following titles to search for the document in a new window using Google Scholar.
Some of these references may be difficult to locate using Google Scholar. If you are having trouble finding the correct reference paper, try searching for it on PubMed: http://www.ncbi.nlm.nih.gov/PubMed
Tyr-MIF-1 attenuates antinociceptive responses induced by three models of stress-analgesia
Z. Harry Galina, Abba J. Kastin
British Journal of Pharmacology
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Antipsychotic activity of standardized Bacopa extract against ketamine-induced experimental psychosis in mice: Evidence for the involvement of dopaminergic, serotonergic, and cholinergic systems
Manavi Chatterjee, Rajkumar Verma, Reena Kumari, Seema Singh, Anil Kumar Verma, Anil Kumar Dwivedi, and Gautam Palit
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Molecular Neurobiology, May 2015
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Molecular Neurobiology, 28 May 2015
Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT1A receptor functional profile
Anna Partyka, Gra?yna Chlon-Rzepa, Anna Wasik, Magdalena Jastrzebska-Wi?sek, Adam Bucki, Marcin Kolaczkowski, Grzegorz Satala, Andrzej J. Bojarski, Anna Wesolowska
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Evaluation of the Antipsychotic Potential of Panax quinquefolium in Ketamine Induced Experimental Psychosis Model in Mice
Manavi Chatterjee, Seema Singh, Reena Kumari, Anil Kumar Verma, Gautam Palit
Neurochemical Research
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The misfolded pro-inflammatory protein S100A9 disrupts memory via neurochemical remodelling instigating an Alzheimer's disease-like cognitive deficit
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Calycosin ameliorates diabetes-induced cognitive impairments in rats by reducing oxidative stress via the PI3K/Akt/GSK-3β signaling pathway
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Neuroprotective Role of Novel Triazine Derivatives by Activating Wnt/β Catenin Signaling Pathway in Rodent Models of Alzheimer’s Disease
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Molecular Neurobiology, September 2014
Chronic decrease in wakefulness and disruption of sleep-wake behavior after experimental traumatic brain injury
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International Journal of Basic & Clinical Pharmacology, Vol. 5, Issue 3, 2016
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Two-Way Shuttlebox Avoidance Conditioning and Brain NADH in Rats
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LP-BM5 infection impairs acquisition, but not performance, of active avoidance responding in C57Bl/6 mice
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Attenuating GABAA Receptor Signaling in Dopamine Neurons Selectively Enhances Reward Learning and Alters Risk Preference in Mice
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The Journal of Neuroscience, 23 November 2011, 31(47): 17103-17112; doi: 10.1523/?JNEUROSCI.1715-11.2011
The Ameliorating Effects of Acute and Chronic Administration of LiuWei
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Ming-Tsuen HSIEH, Sung-Jen CHENG, Li-Wei LIN, Wen-Hsin WANG, and Chi-Rei WU*
Biol. Pharm. Bull. 26(2) 156—161 (2003)
A comparative study in rodents of standardized extracts of Bacopa
monniera and Ginkgo biloba
Anticholinesterase and cognitive enhancing activities
Amitava Dasa, Girja Shankera, Chandishwar Natha, Raghwendra Palb,
Satyawan Singhb, Hemant K. Singha,*
Pharmacology, Biochemistry and Behavior 73 (2002) 893-900
Statistical Parameters in Behavioral Tasks and Implications for Sample Size of C57BL/6J:129S6/SvEvTac Mixed Strain Mice
Sandi Jo Estill
1, Kathleen Fay
1 and Joseph A. Garcia
2
Transgenic Research; Volume 10, Number 2
Date: April 2001 Pages: 157 - 175
Effect of ovariectomy and estrogen supplementation on brain acetylcholinesterase activity and passive-avoidance learning in rats
Amitava Das, Madhu Dikshit, Shoba R. Srivastava, Umesh K. Srivastava, and Chandishwar Nath
Can. J. Physiol. Pharmacol. 80(9): 907-914 (2002)
Novel cognitive improving and neuroprotective activities of Polygala tenuifolia Willdenow extract, BT-11
Cheol Hyoung Park
1, Se Hoon Choi
1, Ja-Wook Koo
2, Ji-Heui Seo
1, Hye-Sun Kim
1, Sung-Jin Jeong
1, Yoo-Hun Suh
1 *
Journal of Neuroscience Research; Volume 70, Issue 3 , Pages 484 - 492
Impaired Cued and Contextual Memory in NPAS2-Deficient Mice
Joseph A. Garcia, Di Zhang, Sandi Jo Estill, Carolyn Michnoff, Jared Rutter, Martin Reick, Kristin Scott, Ramon Diaz-Arrastia, and Steven L. McKnight
Science 23 June 2000:
Vol. 288. no. 5474, pp. 2226 - 2230
Protective Effects of Hippophae rhamnoides L. Juice on Lead-Induced Neurotoxicity in Mice
Yanji Xu
1, Guangzhe Li2), Chunji Han
1, Lianping Sun
3, Rongjie Zhao
3 and Santian Cui
1
Biological & Pharmaceutical Bulletin
Vol. 28 (2005) , No. 3 490
Neonatal ethanol exposure produces a hyperalgesia that extends into adolescence, and is associated with increased analgesic and rewarding properties of nicotine in rats
Dennis T. Rogers
1 , Susan Barron
3 and John M. Littleton
1, 2
Psychopharmacology, Volume 171, Number 2 / January, 2000, Pages 204-211
Dehydroevodiamine·HCl Prevents Impairment of Learning and Memory and Neuronal Loss in Rat Models of Cognitive Disturbance
Cheol Hyoung Park
*, Young-Jae Lee
‡, Sang Hyung Lee
†, Se Hoon Choi
*, Hye-Sun Kim
*, Sung-Jin Jeong
*, Sung Soo Kim
§ & Yoo-Hun Suh
Journal of Neurochemistry, Volume 74 Issue 1 Page 244-253, January 2000
Role of molecular isoforms of acetylcholinesterase in learning and memory functions
Amitava Das1, Madhu Dikshit and Chandishwar Nath
Pharmacology Biochemistry and Behavior
Volume 81, Issue 1, May 2005, Pages 89-99
D2 dopamine receptor blockade prevents cognitive effects of Ang IV and des-Phe6 Ang IV
J.J. Braszko
Physiology & Behavior
Volume 88, Issues 1-2, 15 June 2006, Pages 152-159
An assessment of the long-term developmental and behavioral teratogenicity of prenatal nicotine exposure
Julia Vaglenova
1, Sanjay Birru , Noemi M. Pandiella and Charles R. Breese
Behavioural Brain Research
Volume 150, Issues 1-2, 2 April 2004, Pages 159-170
Adaptogenic and anti-amnesic properties of Evolvulus alsinoides in rodents
Kiran Babu Siripurapua, Prasoon Guptab, Gitika Bhatiac, Rakesh Mauryab, Chandishwar Natha and Gautam Palita
Pharmacology Biochemistry and Behavior
Volume 81, Issue 3, July 2005, Pages 424-432
Aniracetam Reversed Learning and Memory Deficits Following Prenatal Ethanol Exposure by Modulating Functions of Synaptic AMPA Receptors
Julia Vaglenova
1, Noemi Pandiella
1, Nayana Wijayawardhane
1, Tiru Vaithianathan
1, Sandjay Birru
1, Charles Breese
1, Vishnu Suppiramaniam
1 and Clark Randal
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Neuropsychopharmacology (2008) 33, 1071-1083
Effect of insulin and melatonin on acetylcholinesterase activity in the brain of amnesic mice
Rahul Agrawal, Ethika Tyagi, Rakesh Shukla and Chandishwar Nath
Behavioural Brain Research Volume 189, Issue 2, 3 June 2008, Pages 381-386
Gugulipid, an extract of Commiphora whighitii with lipid-lowering properties, has protective effects against streptozotocin-induced memory deficits in mice
Gunjan Saxena, Sheelendra Pratap Singh, Raghvendra Pal, Stayawan Singh, Ram Pratap and Chandishwar Nath
Pharmacology Biochemistry and Behavior Volume 86, Issue 4, April 2007, Pages 797-805
Long-lasting teratogenic effects of nicotine on cognition: Gender specificity and role of AMPA receptor function
J. Vaglenova
a, K. Parameshwaran
a, V. Suppiramaniam
a, C.R. Breese
a, N. Pandiella
a and S. Birru
a
Neurobiology of Learning and Memory
Volume 90, Issue 3, October 2008, Pages 527-536
BT-11 improves stress-induced memory impairments through increment of glucose utilization and total neural cell adhesion molecule levels in rat brains
Ki Young Shin
1, Beom Young Won
2, Chaejeong Heo
3, Hee Jin Kim
1, Dong-Pyo Jang
3, Cheol Hyoung Park
1, Seonghan Kim
1, Hye-Sun Kim
1, Young-Bo Kim
3, Hyung Gun Lee
2, Sang Hyung Lee
4, Zang-Hee Cho
3, Yoo-Hun Suh
1 2 *
Journal of Neuroscience Research
Volume 87 Issue 1, Pages 260 - 268
Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice
Gunjan Saxena
a, Sheelendra Pratap Singh
a, Rahul Agrawal
a and Chandishwar Nath
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European Journal of Pharmacology
Volume 581, Issue 3, 10 March 2008, Pages 283-289
Cholinergic influence on memory stages: A study on scopolamine amnesic mice
Rahul Agrawal, Ethika Tyagi, Gunjan Saxena, Chandishwar Nath
Indian Journal of Pharmacology, Year : 2009 | Volume : 41 | Issue : 4 | Page : 192-196
Neuroprotection Through Rapamycin-Induced Activation of Autophagy and PI3K/Akt1/mTOR/CREB Signaling Against Amyloid-ß-Induced Oxidative Stress, Synaptic/Neurotransmission Dysfunction, and Neurodegeneration in Adult Rats
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Mol Neurobiol (2016). doi:10.1007/s12035-016-0129-3
Dehydroevodiamine·HCl enhances cognitive function in memory-impaired rat models
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Korean J Physiol Pharmacol. 2017 Jan; 21(1):55-64