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Protection against High-Fat-Diet-Induced Obesity in MDM2C305F Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure
Shijie Liu, Tae-Hyung Kim, Derek A. Franklin, Yanping Zhang
Cell Reports, Volume 18, Issue 4, p1005–1018, 24 January 2017
Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat
Philip M. Coan, Oliver Hummel, Ana Garcia Diaz, Marjorie Barrier, Neza Alfazema, Penny J. Norsworthy, Michal Pravenec, Enrico Petretto, Norbert Hübner, Timothy J. Aitman
Disease Models & Mechanisms 2017 10: 297-306; doi: 10.1242/dmm.026716
A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes
Lingling Shu, Ruby L. C. Hoo, Xiaoping Wu, Yong Pan, Ida P. C. Lee, Lai Yee Cheong, Stefan R Bornstein, Xianglu Rong, Jiao Guo & Aimin Xu
Nature Communications 8, Article number: 14147 (2017)
doi:10.1038/ncomms14147
Deletion of p22phox-dependent oxidative stress in the hypothalamus protects against obesity by modulating ß3 - adrenergic mechanisms
Heinrich E. Lob, Jiunn Song, Chansol Hurr, Alvin Chung, Colin N. Young, Allyn L. Mark, and Robin L. Davisson
JCI Insight. 2017;2(2):e87094.
Knocking down amygdalar PTP1B in diet-induced obese rats improves insulin signaling/action, decreases adiposity and may alter anxiety behavior
Natalia Ferreira Mendes, Gisele Castro, Dioze Guadagnini, Natalia Tobar, Susana Quiros Cognuck, Lucila Leico Kagohara Elias, Patricia Aline Boer, Patricia Oliveira Prada
Metabolism, Volume 70, May 2017, Pages 1–11
Pharmacological Inhibition of c-Jun N-terminal Kinase Reduces Food Intake and Sensitizes Leptin’s Anorectic Signaling Actions
Su Gao, Shannon Howard & Philip V. LoGrasso
Scientific Reports 7, Article number: 41795 (2017), doi:10.1038/srep41795
FAK signalling controls insulin sensitivity through regulation of adipocyte survival
Cynthia T. Luk, Sally Yu Shi, Erica P. Cai, Tharini Sivasubramaniyam, Mansa Krishnamurthy, Jara J. Brunt, Stephanie A. Schroer, Daniel A. Winer & Minna Woo
Nature Communications 8, Article number: 14360 (2017), doi:10.1038/ncomms14360
EPRS is a critical mTORC1–S6K1 effector that influences adiposity in mice
Abul Arif, Fulvia Terenzi, Alka A. Potdar, Jie Jia, Jessica Sacks, Arnab China, Dalia Halawani, Kommireddy Vasu, Xiaoxia Li, J. Mark Brown, Jie Chen, Sara C. Kozma, George Thomas & Paul L. Fox
Nature 542, 357–361 (16 February 2017), doi:10.1038/nature21380
17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization
Michael B. Stout, 1 Frederik J. Steyn, 2 Michael J. Jurczak, 3 Joao-Paulo G. Camporez, 4 Yi Zhu, 1 John R. Hawse, 5 Diana Jurk, 6 Allyson K. Palmer, 1 Ming Xu, Tamar Pirtskhalava, Glenda L. Evans, Roberta de Souza Santos, Aaron P. Frank, Thomas A. White, David G. Monroe, Ravinder J. Singh, Grace Casaclang-Verzosa, Jordan D. Miller, Deborah J. Clegg, Nathan K. LeBrasseur, Thomas von Zglinicki, Gerald I. Shulman, Tamara Tchkonia, and James L. Kirkland
J Gerontol A Biol Sci Med Sci. 2017 January; 72(1): 3–15. Published online 2016 January 24. doi:10.1093/gerona/glv309
RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs
Jiexin Wang, Prashant Rajbhandari, Andrey Damianov, Areum Han, Tamer Sallam, Hironori Waki, Claudio J. Villanueva, Stephen D. Lee, Ronni Nielsen, Susanne Mandrup, Karen Reue, Stephen G. Young, Julian Whitelegge, Enrique Saez, Douglas L. Black, and Peter Tontonoz
J Clin Invest. 2017;127(3):987-1004. doi:10.1172/JCI89484.
Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice
Naoto Nagata, Liang Xu, Susumu Kohno, Yusuke Ushida, Yudai Aoki, Ryohei Umeda, Nobuo Fuke, Fen Zhuge, Yinhua Ni, Mayumi Nagashimada, Chiaki Takahashi, Hiroyuki Suganuma, Shuichi Kaneko and Tsuguhito Ota
Diabetes 2017 Feb; db160662. https://doi.org/10.2337/db16-0662
An ATF4/ATG5 Signaling in Hypothalamic POMC Neurons Regulates Fat Mass via Affecting Energy Expenditure
Yuzhong Xiao, Yalan Deng, Feixiang Yuan, Tingting Xia, Hao Liu, Zhigang Li, Zhixue Liu, Hao Ying, Yi Liu, Qiwei Zhai, Shanghai Chen and Feifan Guo
Diabetes 2017 Feb; db161546. https://doi.org/10.2337/db16-1546
Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle
Sofi G. Julien , Sun-Yee Kim , Reinhard Brunmeir, Joanna R. Sinnakannu, Xiaojia Ge, Hongyu Li, Wei Ma, Jadegoud Yaligar, Bhanu Prakash KN, Sendhil S. Velan, Pia V. Röder, Qiongyi Zhang, Choon Kiat Sim, Jingyi Wu, Marta Garcia-Miralles, Mahmoud A. Pouladi, Wei Xie, Craig McFarlane, Weiping Han, Feng Xu
PLOS ONE: Biology, Published: February 16, 2017 https://doi.org/10.1371/journal.pbio.1002597
Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease
Faisal J. Alibhai, Jonathan LaMarre, Cristine J. Reitz, Elena V. Tsimakouridze, Jeffrey T. Kroetsch, Steffen-Sebastian Bolz, Alex Shulman, Samantha Steinberg, Thomas P. Burris, Gavin Y. Oudit
Journal of Molecular and Cellular Cardiology, Volume 105, April 2017, Pages 24–37
Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity
Ryan M. Morrow, Martin Picard, Olga Derbeneva, Jeremy Leipzig, Meagan J. McManus, Gilles Gouspillou, Sébastien Barbat-Artigas, Carlos Dos Santos, Russell T. Hepple, Deborah G. Murdock, and Douglas C. Wallace
PNAS, March 7, 2017 vol. 114 no. 10
Activation of murine pre-proglucagon–producing neurons reduces food intake and body weight
Ronald P. Gaykema, Brandon A. Newmyer, Matteo Ottolini, Vidisha Raje, Daniel M. Warthen, Philip S. Lambeth, Maria Niccum, Ting Yao, Yiru Huang, Ira G. Schulman, Thurl E. Harris, Manoj K. Patel, Kevin W. Williams, and Michael M. Scott
J Clin Invest. 2017;127(3):1031-1045. doi:10.1172/JCI81335.
Hypothalamic over-expression of VGF in the Siberian hamster increases energy expenditure and reduces body weight gain
Jo E. Lewis, John M. Brameld, Phil Hill, Cristina Cocco, Barbara Noli, Gian-Luca Ferri, Perry Barrett, Francis J. P. Ebling, Preeti H. Jethwa
PLOS ONE, Published: February 24, 2017 https://doi.org/10.1371/journal.pone.0172724
Time-restricted feeding on weekdays restricts weight gain: A study using rat models of high-fat diet-induced obesity
Magnus Kringstad Olsen, Man Hung Choi, Bard Kulseng, Chun-Mei Zhao, Duan Chen
Physiology & Behavior, Volume 173, 1 May 2017, Pages 298–304
Awake, long-term intranasal insulin treatment does not affect object memory, odor discrimination, or reversal learning in mice
Genevieve A. Bella, Debra Ann Fadool
Physiology & Behavior
Volume 174, 15 May 2017, Pages 104–113
β-Cell Inactivation of Gpr119 Unmasks Incretin-Dependence of GPR119-Mediated Glucoregulation
Brandon L. Panaro, Grace B. Flock, Jonathan E. Campbell, Jacqueline L. Beaudry, Xiemin Cao and Daniel J. Drucker
Diabetes 2017 Mar; db170017. https://doi.org/10.2337/db17-0017
Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice
Val A. Fajardo, Daniel Gamu, Andrew Mitchell, Darin Bloemberg, Eric Bombardier, Paige J. Chambers, Catherine Bellissimo, Joe Quadrilatero, A. Russell Tupling
PLOS ONE, Published: March 9, 2017
TFE3 regulates whole-body energy metabolism in cooperation with TFEB
Nunzia Pastore, Anna Vainshtein, Tiemo J Klisch, Andrea Armani, Tuong Huynh, Niculin J Herz, Elena V Polishchuk, Marco Sandri, View ORCID ProfileAndrea Ballabio
EMBO Molecular Medicine (2017) e201607204
Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning
Mallikarjun Patil, Bal Krishan Sharma, Sawsan Elattar, Judith Chang, Shweta Kapil, Jinling Yuan and Ande Satyanarayana
Diabetes 2017 Jun; 66(6): 1611-1625.
Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in ß-adrenergic receptor signaling.
Carroll SH, Zhang E, Wang BF, LeClair KB, Rahman A, Cohen DE, Plutzky J, Patwari P, Lee RT
PLoS One. 2017 Mar 14;12(3):e0173823. doi: 10.1371/journal.pone.0173823
Effects of hepatic glycogen on food intake and glucose homeostasis are mediated by the vagus nerve in mice
Iliana López-SoldadoRebeca Fuentes-RomeroJordi DuranJoan J. Guinovart
Diabetologia, June 2017, Volume 60, Issue 6, pp 1076–1083
pNaKtide Attenuates Steatohepatitis and Atherosclerosis by Blocking Na/K-ATPase/ROS Amplification in C57Bl6 and ApoE Knockout Mice Fed a Western Diet
Komal Sodhi, Krithika Srikanthan, Perrine Goguet-Rubio, Alexandra Nichols, Amrita Mallick, Athar Nawab, Rebecca Martin, Preeya T. Shah, Muhammad Chaudhry, Saroj Sigdel, Mehiar El-Hamdani, Jiang Liu, Zijian Xie, Nader G. Abraham & Joseph I. Shapiro
Scientific Reports 7, Article number: 193 (2017), doi:10.1038/s41598-017-00306-5
CL 316, 243 mediated reductions in blood glucose are enhanced in RIP140-/- mice independent of alterations in lipolysis
Willem T. Peppler, Paula M. Miotto, Graham P. Holloway, David C. Wright
Biochemical and Biophysical Research Communications, Volume 486, Issue 2, 29 April 2017, Pages 486–491
The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss
Zhiwei Zhang, Yae Hu, Ruhong Yan, Liang Dong, Yizhi Jiang, Zhichao Zhou, Meng Liu, Tiantian Zhou, Ningzheng Dong & Qingyu Wu
Scientific Reports 7, Article number: 45262 (2017)
A chemical chaperone improves muscle function in mice with a RyR1 mutation
Chang Seok Lee, Amy D. Hanna, Hui Wang, Adan Dagnino-Acosta, Aditya D. Joshi, Mark Knoblauch, Yan Xia, Dimitra K. Georgiou, Jianjun Xu, Cheng Long, Hisayuki Amano, Corey Reynolds, Keke Dong, John C. Martin, William R. Lagor, George G. Rodney, Ergun Sahin, Caroline Sewry & Susan L. Hamilton
Nature Communications 8, Article number: 14659 (2017), doi:10.1038/ncomms14659
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
Gan Liu, Luting Zhou, Hai Zhang, Rong Chen, Ye Zhang, Ling Li, Jun-Yu Lu, Hui Jiang, Dong Liu, Shasha Qi, Ying-Ming Jiang, Kai Yin, Zhifang Xie, Yuguang Shi, Yong Liu, Xuetao Cao, Yu-Xia Chen, Dajin Zou & Weiping J. Zhang
Nature Communications 8, Article number: 14824 (2017)
doi:10.1038/ncomms14824
Mfn2 is critical for brown adipose tissue thermogenic function
Marie Boutant, Sameer S Kulkarni, Magali Joffraud, Joanna Ratajczak, Miriam Valera-Alberni, Roy Combe, Antonio Zorzano, Carles Canto
The EMBO Journal (2017) e201694914
Maternal Retinoids Increase PDGFRα+ Progenitor Population and Beige Adipogenesis in Progeny by Stimulating Vascular Development
Bo Wang, Xing Fu, Xingwei Liang, Zhixiu Wang, Qiyuan Yang, Tiande Zou, Wei Nie, Junxing Zhao, Pengfei Gao, Mei-Jun Zhu, Jeanene M. de Avila, Joseph Maricelli, Buel D. Rodgers, Min Du
EBioMedicine 18 (2017) 288–299
Brazilian Green Propolis Promotes Weight Loss and Reduces Fat Accumulation in C57BL/6 Mice Fed A High-Fat Diet
Tohru Sakai, Miyuki Ohhata, Misaki Fujii, Sayaka Oda, Yasuna Kusaka, Miki Matsumoto, Akiko Nakamoto, Tomoyo Taki, Mariko Nakamoto, Emi Shuto
Biological and Pharmaceutical Bulletin, Vol. 40 (2017) No. 4 p. 391-395
p53-upregulated-modulatorof-apoptosis
(PUMA) deficiency
affects food intake but does not
impact on body weight or glucose
homeostasis in diet-induced
obesity
SaraA. Litwak, Kim Loh, William J. Stanley, EvanG. Pappas, JibranA.Wali, Claudia Selck, Andreas Strasser, Helen E.Thomas & Esteban N.Gurzov>br />Scientific Reports | 6:23802 | DOI: 10.1038/srep23802
Endothelial LRP1 regulates metabolic responses by acting as a co-activator of PPARγ
Hua Mao, Pamela Lockyer, Luge Li, Christie M. Ballantyne, Cam Patterson, Liang Xie & Xinchun Pi
Nature Communications 8, Article number: 14960 (2017), doi:10.1038/ncomms14960
Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-Β oligomers in mice
Grasielle C. Kincheski, Isabela S. Valentim, Julia R. Clarke, Danielle Cozachenco, Morgana T.L. Castelo-Branco, Angela M. Ramos-Lobo, Vivian M.B.D. Rumjanek, José Donato Jr., Fernanda G. De Felice, Sergio T. Ferreira
Brain, Behavior, and Immunity, Volume 64, August 2017, Pages 140-151
Dietary lactalbumin and lactoferrin interact with inulin to modulate energy balance in obese rats
Arashdeep Singh, Rizaldy C. Zapata, Adel Pezeshki, Prasanth K. Chelikani
Obesity, Volume 25, Issue 6, June 2017, Pages 1050–1060
SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis
Yanhui Zhang, Litao Xie, Susheel K. Gunasekar, Dan Tong, Anil Mishra, William J. Gibson, Chuansong Wang, Trevor Fidler, Brodie Marthaler, Aloysius Klingelhutz, E. Dale Abel, Isaac Samuel, Jessica K. Smith, Lei Cao & Rajan Sah
Nature Cell Biology 19, 504–517 (2017), doi:10.1038/ncb3514
Deletion of Gpr55 Results in Subtle Effects on Energy Metabolism, Motor Activity and Thermal Pain Sensation
Mikael Bjursell, Erik Ryberg, Tingting Wu, Peter J. Greasley, Mohammad Bohlooly-Y, Stephan Hjorth
PLOS ONE, December 12, 2016, http://dx.doi.org/10.1371/journal.pone.0167965
Early developmental disruption of type 2 deiodinase pathway in mouse skeletal muscle does not impair muscle function
Dr. Danielle Leao Ignacio, Ms. Diego Henrique Silvestre, Miss Elena Palmer, Miss Barbara Bocco, Dr. Tatiana Fonseca, Prof. Balazs Gereben, Dr. Miriam Ribeiro, Dr. Antonio Carlos Bianco, and Prof. Joao Pedro Werneck de Castro
Thyroid. December 2016, ahead of print. doi:10.1089/thy.2016.0392.
Phospholipase D1 deficiency in mice causes nonalcoholic fatty liver disease via an autophagy defect
Jang Ho Hur, Shi-Young Park, Claudia Dall’Armi, Jae Sung Lee, Gilbert Di Paolo, Hui-Young Lee, Mee-Sup Yoon, Do Sik Min & Cheol Soo Choi
Scientific Reports 6, Article number: 39170 (2016), doi:10.1038/srep39170
Dietary Macronutrient Composition Directs ChREBP Isoform Expression and Glucose Metabolism in Mice
Tara Jois, Victor Howard, Kristina Youngs, Michael A. Cowley, Mark W. Sleeman
PLOS ONE, December 19, 2016 http://dx.doi.org/10.1371/journal.pone.0168797
Deletion of ATF4 in AgRP Neurons Promotes Fat Loss Mainly via Increasing Energy Expenditure
Jiali Deng, Feixiang Yuan, Yajie Guo, Yuzhong Xiao, Yuguo Niu, Yalan Deng, Xiao Han, Youfei Guan, Shanghai Chen, Feifan Guo
Diabetes 2016 Dec; db160954. https://doi.org/10.2337/db16-0954
Gsα deficiency in the dorsomedial hypothalamus underlies obesity associated with Gsα mutations
Min Chen, Yogendra B. Shrestha, Brandon Podyma, Zhenzhong Cui, Benedetta Naglieri, Hui Sun, Thuy Ho, Eric A. Wilson, Yong-Qi Li, Oksana Gavrilova, and Lee S. Weinstein
J Clin Invest. 2016. doi:10.1172/JCI88622
Coffee consumption in aged mice increases energy production and decreased hepatic mTOR levels
Keita Takahashi, Shuichi Yanai, Kentaro Shimokado, Akihito Ishigami
Nutrition, Available online 7 January 2017
Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism
Heather A. Ferris, Rachel J. Perry, Gabriela V. Moreira, Gerald I. Shulmanb, Jay D. Horton, and C. Ronald Kahn
PNAS January 17, 2017
Brown Adipogenic Reprogramming Induced by a Small Molecule
Baoming Nie, Tao Nie, Xiaoyan Hui, Ping Gu, Liufeng Mao, Kuai Li, Ran Yuan, Jiashun Zheng, Haixia Wang, Ke Li, Shibing Tang, Yu Zhang, Tao Xu, Aimin Xu, Donghai Wu, Sheng Ding
Cell Reports, Volume 18, Issue 3, 17 January 2017, Pages 624–635
Chronic Maternal Low-Protein Diet in Mice Affects Anxiety, Night-Time Energy Expenditure and Sleep Patterns, but Not Circadian Rhythm in Male Offspring
Randy F. Crossland , Alfred Balasa , Rajesh Ramakrishnan, Sangeetha K. Mahadevan, Marta L. Fiorotto, Ignatia B. Van den Veyver
PLOS ONE, Published: January 18, 2017
Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice
Aaron M. Gusdon, Jason Callio, Giovanna DiStefano, Robert M. O'Doherty, Bret H. Goodpaster, Paul M. Coen, Charleen T. Chu
Experimental Gerontology, Available online 18 January 2017
De novo sphingolipid biosynthesis is required for adipocyte survival and metabolic homeostasis
Aikaterini Alexaki, Benjamin A. Clarke, Oksana Gavrilova, Yinyan Ma, Hongling Zhu, Xinran Ma, Lingyan Xu, Galina Tuymetova, Bridget C. Larman, Maria L. Allende, Teresa M. Dunn and Richard L. Proia
The Journal of Biological Chemistry, January 18, 2017, doi: 10.1074/jbc.M116.756460
Increases in Physical Activity Result in Diminishing Increments in Daily Energy Expenditure in Mice
Timothy J. O’Neal, Danielle M. Friend, Juen Guo, Kevin D. Hall, Alexxai V. Kravitz
Current Biology, Available online 19 January 2017
Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance
Babu Nageswararao Kanuri, Jitendra S. Kanshana, Sanjay C. Rebello, Priya Pathak, Anand P. Gupta, Jiaur R. Gayen, Kumaravelu Jagavelu & Madhu Dikshit
Scientific Reports 7, Article number: 41009
The nutrient sensor OGT in PVN neurons regulates feeding
Olof Lagerlöf, Julia E. Slocomb, Ingie Hong, Yeka Aponte, Seth Blackshaw, Gerald W. Hart, Richard L. Huganir
18 March 2016, Science 351, 1293 (2016) DOI: 10.1126/science.aad5494
Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high-fat-fed ovariectomized mice
Dale J. Hamilton, Laurie J. Minze, Tanvi Kumar, Tram N. Cao, Christopher J. Lyon, Paige C. Geiger, Willa A. Hsueh, Anisha A. Gupte
Physiological Reports Published 30 August 2016 Vol. 4 no. e12913 DOI: 10.14814/phy2.12913
Epigenomic and metabolic responses of hypothalamic POMC neurons to gestational nicotine exposure in adult offspr
Jose P. SilvaEmail author, Guerline Lambert, Derek van Booven and Claes Wahlestedt
Genome Medicine, 2016, 8:93, DOI: 10.1186/s13073-016-0348-2
Sox21 deletion in mice causes postnatal growth deficiency without physiological disruption of hypothalamic-pituitary endocrine axes
Leonard Y.M. Cheung, Hideyuki Okano, Sally A. Camper
Molecular and Cellular Endocrinology, Available online 8 September 2016
Neuronal Rap1 Regulates Energy Balance, Glucose Homeostasis, and Leptin Actions
Kentaro Kaneko, Pingwen Xu, Elizabeth L. Cordonier, Siyu S. Chen, Amy Ng, Yong Xu, Alexei Morozov, Makoto Fukuda
Cell Reports, Volume 16, Issue 11, 13 September 2016, Pages 3003–3015
Reevaluation of anti-obesity action of mazindol and elucidation of its effect on the reward system
Daisuke Aotani, Cheol Son, Yoshiyuki Shimizu, Hidenari Nomura, Takatoshi Hikida, Toru Kusakabe, Tomohiro Tanaka, Takashi Miyazawa, Kiminori Hosoda, Kazuwa Nakao
Neuroscience Letters, Volume 633, 28 October 2016, Pages 141–145
Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity
Heekyung Chung, Winjet Chou, Dorothy D. Sears, Ruth E. Patterson, Nicholas J.G. Webster, Lesley G. Ellies
Metabolism
Volume 65, Issue 12, December 2016, Pages 1743–1754
One-time injection of AAV8 encoding urocortin 2 provides long-term resolution of insulin resistance
Mei Hua Gao, Dimosthenis Giamouridis, N. Chin Lai, Evelyn Walenta, Vivian Almeida Paschoal, Young Chul Kim, Atsushi Miyanohara, Tracy Guo, Min Liao, Li Liu, Zhen Tan, Theodore P. Ciaraldi, Simon Schenk, Aditi Bhargava, Da Young Oh, and H. Kirk Hammond
JCI Insight. 2016;1(15):e88322. doi:10.1172/jci.insight.88322.
Loss of ZBTB20 impairs circadian output and leads to unimodal behavioral rhythms
Zhipeng Qu, Hai Zhang, Moli Huang, Guangsen Shi, Zhiwei Liu, Pancheng Xie, Hui Li, Wei Wang, Guoqiang Xu, Yang Zhang, Ling Yang, Guocun Huang, Joseph S Takahashi, Weiping J Zhang, Ying Xu
eLife 2016;5:e17171
A beta cell ATGL-lipolysis/adipose tissue axis controls energy homeostasis and body weight via insulin secretion in mice
Camille AttanéMarie-Line Peyot, Roxane Lussier, Pegah Poursharifi, Shangang Zhao, Dongwei Zhang, Johane Morin, Marco Pineda, Shupei Wang, Olivier Dumortier, Neil B. Ruderman, Grant A. Mitchell, Brigitte Simons, S. R. Murthy Madiraju, Erik Joly, Marc Prentki
Diabetologia (2016). doi:10.1007/s00125-016-4105-2
Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing
Elisa Giorgetti, Zhigang Yu, Jason P. Chua, Ryosuke Shimamura, Lili Zhao, Fan Zhu, Sriram Venneti, Maria Pennuto, Yuanfang Guan, Gene Hung, Andrew P. Lieberman
Cell Reports, Volume 17, Issue 1, 27 September 2016, Pages 125–136
Calorie restriction protects against experimental abdominal aortic aneurysms in mice
Yue Liu, Ting-Ting Wang, Ran Zhang, Wen-Yan Fu, Xu Wang, Fang Wang, Peng Gao, Yang-Nan Ding, Yan Xie, De-Long Hao, Hou-Zao Chen, De-Pei Liu
Journal of Experimental Medicine Sep 2016, jem.20151794; DOI: 10.1084/jem.20151794
Metabolic Fate of Branched-Chain Amino Acids During Adipogenesis, in Adipocytes from Obese Mice and C2C12 Myotubes
Isabela Estrada-Alcalde, Miriam R. Tenorio-Guzman, Armando R. Tovar, Daniela Salinas-Rubio, Ivan Torre-Villalvazo, Nimbe Torres, Lilia G. Noriega
J. Cell. Biochem. 30 September 2016. Accepted Author Manuscript. doi:10.1002/jcb.25755
Novel Role for Matrix Metalloproteinase 9 in Modulation of Cholesterol Metabolism
Samuel Hernandez-Anzaldo, Vesna Brglez, Bianca Hemmeryckx, Dickson Leung, Janos G. Filep, Jean E. Vance, Dennis E. Vance, Zamaneh Kassiri, Roger H. Lijnen, Gérard Lambeau, Carlos Fernandez-Patron
J Am Heart Assoc. 2016; 5: e004228
Aguamiel concentrate from Agave salmiana and its extracted saponins attenuated obesity and hepatic steatosis and increased Akkermansia muciniphila in C57BL6 mice
Ana María Leal-Díaz, Lilia G. Noriega, Ivan Torre-Villalvazo, Nimbe Torres, Gabriela Alemán-Escondrillas, Patricia López-Romero, Mónica Sánchez-Tapia, Miriam Aguilar-López, Janette Furuzawa-Carballeda, Laura A. Velázquez-Villegas, Azalia Avila-Nava, Guillermo Ordáz, Janet A. Gutiérrez-Uribe, Sergio O. Serna-Saldivar & Armando R. Tovar
Scientific Reports 6, Article number: 34242 (2016) doi:10.1038/srep34242
Maternal high-fat diet during lactation impairs thermogenic function of brown adipose tissue in offspring mice
Xingwei Liang, Qiyuan Yang, Lupei Zhang, Joseph W Maricelli, Buel D. Rodgers, Mei-Jun Zhu & Min Du
Scientific Reports 6, Article number: 34345 (2016) doi:10.1038/srep34345
A cholinergic basal forebrain feeding circuit modulates appetite suppression
Alexander M. Herman, Joshua Ortiz-Guzman, Mikhail Kochukov, Isabella Herman, Kathleen B. Quast, Jay M. Patel, Burak Tepe, Jeffrey C. Carlson, Kevin Ung, Jennifer Selever, Qingchun Tong & Benjamin R. Arenkiel
Nature 538, 253–256 (13 October 2016) doi:10.1038/nature19789
Adipocyte-specific deletion of Ip6k1 reduces diet-induced obesity by enhancing AMPK-mediated thermogenesis
Qingzhang Zhu, Sarbani Ghoshal, Ana Rodrigues, Su Gao, Alice Asterian, Theodore M. Kamenecka, James C. Barrow, and Anutosh Chakraborty
J Clin Invest. 2016. doi:10.1172/JCI85510.
Nat1 Deficiency Is Associated with Mitochondrial Dysfunction and Exercise Intolerance in Mice
Indumathi Chennamsetty, Michael Coronado, Kevin Contrepois, Daniel Bernstein, Thomas Quertermous, Joshua W. Knowles
Cell Reports 17, 527–540 October 4, 2016
Adipose HIF-1a causes obesity by suppressing brown adipose tissue thermogenesis
Jonathan C. Jun, Ronald Devera, Dileep Unnikrishnan, Mi-Kyung Shin, Shannon Bevans-Fonti, Qiaoling Yao, Aman Rathore, Haris Younas, Nils Halberg, Philipp E. Scherer, Vsevolod Y. Polotsky
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Pharmacologic activation of estrogen receptor ß increases mitochondrial function, energy expenditure, and brown adipose tissue
Suriyan Ponnusamy, Quynh T. Tran, Innocence Harvey, Heather S. Smallwood, Thirumagal Thiyagarajan, Souvik Banerjee, Daniel L. Johnson, James T. Dalton, Ryan D. Sullivan, Duane D. Miller, Dave Bridges, and Ramesh Narayanan
FASEB J fj.201600787RR; published ahead of print October 12, 2016, doi:10.1096/fj.201600787RR
Suboptimal nutrition in early life affects the inflammatory gene expression profile and behavioral responses to stressors
Nicola M. Grissoma, Robert Georgeb, Teresa M. Reyes
Brain, Behavior, and Immunity, Available online 15 October 2016
Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance
Max C. Petersen, Anila K. Madiraju, Brandon M. Gassaway, Michael Marcel, Ali R. Nasiri, Gina Butrico, Melissa J. Marcucci, Dongyan Zhang, Abudukadier Abulizi, Xian-Man Zhang, William Philbrick, Stevan R. Hubbard, Michael J. Jurczak, Varman T. Samuel, Jesse Rinehart, and Gerald I. Shulman
J Clin Invest. 2016. doi:10.1172/JCI86013.
Reduction of p38 mitogen-activated protein kinase and cyclooxygenase-2 signaling by isoflurane inhibits proliferation and apoptosis evasion in human papillomavirus-infected laryngeal papillomas
Hongbo Ren Xiaojuan Shi Ying Li
Experimental and Therapeutic Medicine, 12, 3425-3432. http://dx.doi.org/10.3892/etm.2016.3776
Diets Containing Shiitake Mushroom Reduce Serum Lipids and Serum Lipophilic Antioxidant Capacity in Rats
Shanggong Yu, Xianli Wu, Matthew Ferguson, Rosalia CM Simmen, Mario A Cleves, Frank A Simmen, and Nianbai Fang
The Journal of Nutrition, October 19, 2016, doi: 10.3945/?jn.116.239806
Ambient temperature modulates the effects of the Prader-Willi syndrome candidate gene Snord116 on energy homeostasis
Y. Qi, L. Purtell, M. Fu, K. Sengmany, K. Loh, L. Zhang, S. Zolotukhin, A. Sainsbury, L. Campbell, & H. Herzog
Neuropeptides, Available online 27 October 2016
Ablation of PPP1R3G reduces glycogen deposition and mitigates high-fat diet induced obesity
Yongxian Zhang, Jin Gu, Lin Wang, Zilong Zhao, Yi Pan, Yan Chen
Molecular and Cellular Endocrinology , Volume 439, 5 January 2017, Pages 133–140
Linoleic acid causes greater weight gain than saturated fat without hypothalamic inflammation in the male mouse
Kyle J. Mamounis, Ali Yasrebi, Troy A. Roepke
The Journal of Nutritional Biochemistry, Volume 40, February 2017, Pages 122–131
Weight gain in mice on a high caloric diet and chronically treated with omeprazole depends on sex and genetic background
Milena Saqui-Salces, Amy C. Tsao, Merritt G. Gillilland III, Juanita L. Merchant
American Journal of Physiology - Gastrointestinal and Liver Physiology Published 3 November 2016 Vol. no. , DOI: 10.1152/ajpgi.00211.2016
Partial deficiency of CTRP12 alters hepatic lipid metabolism
Stefanie Y Tan, Hannah C. Little, Xia Lei, Shuoyang Li, Susana Rodriguez, G. William Wong
Physiological Genomics Published 4 November 2016 Vol. no. , DOI: 10.1152/physiolgenomics.00111.2016
Harmine Induces Adipocyte Thermogenesis through RAC1-MEK-ERK-CHD4 Axis
Tao Nie, Xiaoyan Hui, Liufeng Mao, Baoming Nie, Kuai Li, Wei Sun, Xuefei Gao, Xiaofeng Tang, Yong Xu, Baishan Jiang, Zhengcao Tu, Peng Li, Ke Ding, Weiping Han, Shaoping Zhang, Aimin Xu, Sheng Ding, Pentao Liu, Adam Patterson, Garth Cooper & Donghai Wu
Scientific Reports 6, Article number: 36382, 12 October 2016, doi:10.1038/srep36382
Macrophage Proliferation Sustains Adipose Tissue Inflammation in Formerly Obese Mice
Brian F. Zamarron, Taleen A. Mergian, Kae Won Cho, Gabriel Martinez-Santibanez, Danny Luan, Kanakadurga Singer, Jennifer L. DelProposto, Lynn M. Geletka, Lindsey A. Muir, Carey N. Lumeng
Diabetes 2016 Nov; db160500. http://dx.doi.org/10.2337/db16-0500
Intestinal PPARγ signalling is required for sympathetic nervous system activation in response to caloric restriction
Kalina Duszka, Alexandre Picard, Sandrine Ellero-Simatos, Jiapeng Chen, Marianne Defernez, Eeswari Paramalingam, Anna Pigram, Liviu Vanoaica, Cécile Canlet, Paolo Parini, Arjan Narbad, Hervé Guillou, Bernard Thorens & Walter Wahli
Scientific Reports 6, Article number: 36937, 05 October 2016, doi:10.1038/srep36937
Testosterone Rapidly Augments Retrograde Endocannabinoid Signaling in Proopiomelanocortin Neurons to Suppress Glutamatergic Input from Steroidogenic Factor-1 Neurons via Upregulation of Diacylglycerol Lipase-α
Conde K · Fabelo C. · Krause W.C. · Propst R. · Goethel J. · Fischer D. · Hur J. · Meza C. · Ingraham H.A. · Wagner E.J.
Neuroendocrinology, 2016 Nov 21, DOI: 10.1159/000453370
Hepatic inositol 1,4,5 trisphosphate receptor type 1 mediates fatty liver
Colleen N. Feriod, Andre Gustavo Oliveira, Mateus T. Guerra, Lily Nguyen,
Kisha Mitchell Richards, Michael J. Jurczak, Hai-Bin Ruan, Joao Paulo Camporez, Xiaoyong Yang, Gerald I. Shulman, Anton M. Bennett, Michael H. Nathanson, Barbara E. Ehrlich
Hepatology Communications, 11 November 2016, doi:10.1002/hep4.1012
Deletion of the Vesicular Acetylcholine Transporter from Pedunculopontine/laterodorsal tegmental neurons modifies gait
Helena Janickova, Kaie Rosborough, Mohammed Al-Onaizi, Ornela Kljakic,
Monica S. Guzman, Robert Gros, Marco A.M. Prado, Vania F. Prado
J. Neurochem. 27 November 2016. doi:10.1111/jnc.13910
Genetic Ablation of Phosphatidylcholine Transfer Protein/StarD2 in ob/ob Mice Improves Glucose Tolerance Without Increasing Energy Expenditure
Tibor I. Krisko, Katherine B. LeClair, David E. Cohen
Metabolism
1 December 2016
The Hypothalamic Glucagon-Like Peptide-1 (GLP-1) Receptor (GLP-1R) is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice
Melissa A. Burmeister, Jennifer E. Ayala, Hannah Smouse, Adriana Landivar-Rocha, Jacob D. Brown, Daniel J. Drucker, Doris A. Stoffers, Darleen A. Sandoval, Randy J. Seeley, Julio E. Ayala
Diabetes 2016 Dec; db161102. http://dx.doi.org/10.2337/db16-1102